ESPE Abstracts

Background: The non-physiological ways and supraphysiological doses of insulin required for good glycemic control in patients with type 1 diabetes right from onset exposes them to effects of hyperinsulinism. In addition insulin resistance may be seen because of glucose toxicity and abnormal fat mass gain during puberty Insulin acts synergistically with luetinizing hormone to facilitate androgen production by theca.Objective and hypotheses: To investigate...

Introduction: Glucose tolerance and beta cell function can be abnormal in polycystic ovary syndrome (PCOS) patients because of obesity and/or PCOS per se.Methods: Various indices derived from 2 hours oral glucose tolerance test (OGTT) were compared in 46 adolescents with PCOS (mean age 17.6 +1.9 years and mean body mass index (BMI) 24.5 +5.4 kg/m2) with age comparable controls (n=25, mean ...

Introduction: In India, newborn screening (NBS) for congenital hypothyroidism (CH) is not yet a national government policy. Preliminary information suggests neonatal TSH levels to be higher in expatriate Indian babies than those in European populations in developed countries.Objectives: To evaluate maternal urinary iodine and cord blood TSH in a subset of women participating in a postnatal NBS program for CH.Methods: Cord blood (CB...